The SMARTube™:

The SMARTube is a blood sample processing device containing a proprietary activation media for the stimulation of antibody production (In-Vitro). It is a complementary product for improving the performance of standard serological assays by reducing the rate of both false-positive and false-negative results. SMARTube enables detection of infections during the “window period” (when the standard serology is negative), enables validation of a positive infection, and also effectively distinguishes between various stages of infection: acute, chronic, active, or viral cleared/resolved infection (be it spontaneous or drug elicited), while the standard serological test cannot produce this information.

The SMARTube is based on the company’s proprietary platform technology, Stimmunology™ allowing the growth and differentiation of primed lymphocytes (sensitized lymphocytes that have been exposed to the virus) that are present in the patient’s whole blood sample. It includes an activation media in which whole blood lymphocytes are stimulated to produce virus-specific antibodies in-vitro within days. Stimmunology is overcoming the immune suppression of the body and thus, antibodies which were not present or detected in the original sample would be present and detectable in the enhanced samples following the Stimmunology incubation.

The Products:
SMARTube has developed three products: SMARTube™HCV, SMARTube™HIV and combined SMARTube™HIV&HCV. The company conducted clinical trials with these products in various countries around the world (such as the USA, Israel, Russia, China, South Africa, Kenya, Mexico, and Confidential 3 others). The results of these clinical trials have been published in both peer-reviewed journals and international conferences. The products’ effectiveness was clinically proven in various serological assays, enabling its integration with any serological assay. The SMARTube™ HIV&HCV has received the CE mark as well as regulatory clearance in several other countries. The SMARTube™HIV is currently in the regulatory clearance process with the US Food and Drug Administration (“FDA”). SMARTube works in collaboration with prominent academic institutes such as the University of Maryland and New York University as well as with the U.S Military and other governmental health organizations.